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In an era when trust in just about every institution is waning, the confidence held by the public in researchers and politicians to validate the safety and efficacy of a Covid-19 vaccine is not unsurprisingly, under scrutiny.
Concerns about vaccine safety already exist and should not be dismissed simply as ignorant or “anti-science.” It is quite reasonable that public health scientists and people offered the vaccine want to have a high consistency in analysis and safety data and significant comfort in efficacy vs risk. For if the global population is to be offered a vaccine, or vaccines, even a small percentage of adverse reactions or a limited protective response will negate any viable uptake, potentially extending the period before natural herd immunity can confer some sense of control for years.
Because the beneficial impact of vaccines requires widespread public acceptance to achieve population-level immunity, as well as individual immune systems capable of responding appropriately, vaccination policies from their earliest days have been subject to political and ideological debate, pitting individual rights against public health, referred to as vaccine hesitancy. Read the rest of this entry »
There is an old saying that we have seen which is very applicable to a number of positions held by various groups:
‘You can’t reason someone out of a position they didn’t reason themselves into’.
What do we mean?
Obviously, ongoing challenges across all aspects of comprehension with the Covid-19 pandemic has spurred numerous opinion pieces (including our own), polarised groups into entrenched positions and created a tsunami of conspiracy theories, and a small number of potential clinical interventions (so far), some of which appear to be viable, safe and effective, others less so. Read the rest of this entry »
It is a matter of ongoing review that different countries have experienced different levels of infection with SARS-Cov-2. Some had had very low rates to date with a similarly adjusted associated loss of life and others such as the USA, UK and India have had high levels of infection and associated loss of life.
The results of the new study, published (July 21 2020) in JAMA Internal Medicine suggest that, despite the rising numbers, the infection rate suggested to be necessary for herd immunity has yet to be reached. However, the data indicates that many of these people likely had no symptoms or mild illness and may have had no idea that they were infected. The authors indicate that as many as 40% have been without symptoms while the symptoms brought on by the disease can be highly variable.
Existing immune competence, viral load and other elements previously discussed are suggested as reasons for such a high asymptomatic level and the related number needed to be exposed to determine the gradual collapse in new cases is accordingly adjustable. Read the rest of this entry »
Whilst the subject of viral disease is by virtue of the time span since Jan 2020 somewhat overcovered in musings as well as science reviews, each month brings new clarity on the intersecting health and economic risks of a global pandemic.
The SARS-Cov-2 virus is a recognised threat to billions of people around the world, with the risk being compounded for people who live in overcrowded homes, who don’t have access to safe drinking water or nutritious food and are obese. Other risk factors are also relevant but being overweight, according to one of the largest UK studies on the Covid-19 mortality rate to date from Glasgow University, found that as a patient’s Body Mass Index (BMI) increases, so does their risk of having a severe case of the virus. Obesity is a chronic inflammatory disease and it starts with an inflammation in adipose tissue, or body fat. Researchers have proposed there may be a link between this inflammation and an immune system response in Covid-19 patients ultimately manifesting in the terminal induction of the “cytokine storm”. Read the rest of this entry »
Few will have missed the photograph of Boris Johnson this week (June 29th, 2020), allegedly performing push ups in No 10. Ostensibly demonstrating his intent to modify his body shape considering his well-publicised experience of the symptomatic response to Sars-Cov-2 infecting many of his cells.
Prior to this, a number of the established newspapers also heavily indicated that there was going to be a top down approach to steer people away from practices that foments weight gain, to weight management and where appropriate loss and a healthier lifestyle. Read the rest of this entry »
It is becoming clear that, whilst checking for the usual suspects in effective immune defence against Sars-Cov-2 viral infection includes IgG and IgA and IgM, other mechanisms embedded in our innate and adaptive immune systems may also be at work protecting you.
Pre-infection, there already exists a range of defence strategies your immune system holds ready to deploy, and as has been discussed and explored to date (in prior e-news), it seems that not everyone exposed contracts the virus at a level that induces symptoms, or indeed even contracts the virus at all. Viral load, length of exposure, indoor/outdoor and existing state of health and immune competence all intersect to provide a ‘shield’ of resistance/resilience. Read the rest of this entry »
First let me apologise on behalf of all practitioners and clients for the product outages we are experiencing at Nutri-Link. We know how frustrating it is to find your favoured supplement is not available and more so during times of increased need. Without exhausting your patience on explanations, supply line problems, manufacturing slow downs and raw material supplies have all been part of the Coronavirus challenge. Add to that a significant increase in demand and regrettably we have been unable to meet everyone’s needs.
The changes required to resolve this are coming through, quickly and efficiently and we are expecting that back orders and manufacturing will be catching up very soon. Thank you for your continued loyalty and support, we really appreciate it. Read the rest of this entry »
The current COVID-19 pandemic has numerous actors on a global scale seeking a resolution, in effect a search for the solution to the viral infection that is dominating headlines and many global resources. Leaders in Western countries (and elsewhere) favour vaccination and despite being advised that typical vaccine development and testing can take between 18 months and forever are also suggesting (hoping) that, due to new mechanisms employed in vaccinology, that we will be offered vaccination against SARS-Cov-2 by the end of 2020!
At the time of writing there are eight vaccines worldwide that have begun human testing; managing the outcomes and ensuring no loss in vaccine confidence in the general population will be a serious risk if not managed well. The USA’s announcement of a ‘warp speed’ effort should appeal to those who have an attachment to Star Trek, but raises numerous questions around viability amongst scientists and ultimately consumers. Read the rest of this entry »
Perhaps you have started to envision what life will be like in the coming weeks and months, as countries start to transition away from the ‘lockdown’ status that many, including the UK has undertaken. It may be that looking ahead leaves you cautiously optimistic, anxious and worried, frustrated or relieved when considering all the different elements of your work and home life.
Certainly, its somewhat of an unknown project for all of us and with that comes uncertainty. Most people feel unsettled by uncertainty and for obvious reasons. Yet it also allows for opportunity and development, changes in patterns long enshrined in time constrained lives and perhaps a fresh consideration about what your priorities are going to be for the coming months and possibly years. Read the rest of this entry »
Covid-19, why is it that people manifest such differences in their response to infection? Why is it so impossible (at least at present) to predict an individual’s experience?
The consequences as we have seen and read about of being diagnosed with Covid-19 appears to come with a wide range of risks and symptom intensity. Read the rest of this entry »