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The understanding of what goes wrong in autoimmune disease, and why, is advancing on numerous fronts. One key question that remains, is what makes some people more likely to experience autoimmunity than others?
Gender appears to play a significant part, with autoimmune disease around three times more common in women than in men, with two primary reasons being hormones and chromosomal variations. Read the rest of this entry »
Faced as we are with an infectious and mutating agent of illness, the allied focus on nutritional needs has been to identify foods and nutritional concentrates that confer an immunological advantage. Covid-19 does not treat us equally. Undernourished people have weaker immune systems and may be at greater risk of severe illness due to the virus.
Because iron deficiency degrades non-specific immunity, your body’s first line of defence against pathogens, you are more vulnerable to infection and disease, and other health complications. In fact, frequent infections are a lesser-known symptom of iron deficiency. At the same time, poor metabolic health, including obesity and diabetes, is strongly linked to worse Covid-19 outcomes, including risk of hospitalisation and death. Read the rest of this entry »
Sars-Cov-2 hit at an inauspicious geo-political and geo-environmental moment.
An era of rising nationalism and populism made it frustratingly difficult to mount a collaborative response to a global pandemic. Jair Bolsonaro of Brazil, Xi Jinping of China, Narendra Modi of India, Vladimir Putin of Russia, Recep Tayyip Erdogan of Turkey, Boris Johnson of the United Kingdom, and Donald Trump of the United States stand out. All these leaders (and their executive teams) evinced some combination of parochialism and political insecurity or ideology, which caused them to initially downplay the crisis, ignore the science, or deny its viability, and reject essential international cooperation whilst favouring corporate interests. This ensured their slow and ineffective roll out of immediate viral strategic control. Leading to significant adverse consequences driven by internal political narratives (self or party-protectionism) rather than globally focussed health care. Read the rest of this entry »
As we in the UK move to a progressively relaxed series of social constraints, many are focussing on their proposed re-engagement with previous patterns of work and social life, others are seeking to hybridise their futures, and some have taken the opportunity to re-invent.
Many however, have experienced a change in circumstance and health status so profound, that they can see no easy way to reconnect with a life filled with potential or at least a life that they previously coped with. This appears to be especially true in the arena of mental health, social engagement, and the attainment of internal contentment. Read the rest of this entry »
The source of the Sars-Cov-2 virus has to date been suggested to have either ‘spilled’ over from wildlife to humans, i.e bat to human transmission (zoonotic), or to have emerged, without direct animal transfer from a virology research lab in Wuhan China. Other proposals of origination have yet to make their way into collective consciousness, but no doubt there are some lurking at the edge of plausibility! The research community already accepts that ‘natural spillovers’ occur, these have been recorded for many decades, and highlighted in books and journals that they can cause dangerous and transmissible outbreaks, so scientists do not need any further proof for this proposal. Read the rest of this entry »
“The random scattered errors (noise) in our judgments are at least as damaging and common as the predictable, non-random errors (bias) in them, and the same may be applied to how our immune system is capable of responding to Sars-Cov-2”.
Humans are unreliable decision makers; their judgments are strongly influenced by irrelevant factors, such as their current mood, the time since their last meal, their social experiences, inherited patterns of analysis and the weather. The immune system is also subject to noise; time of the day, body mass, nutrition, medication, inflammation, oxidation, trauma, stress, environment, age etc. Read the rest of this entry »
An article in the British Journal of General Practice published online, on the 29th April 2021, sets out a mixture of support, disdain and implied ineffectiveness of the role that lifestyle medicine has in the restoration and generation of human health. The direct journal response online allows only for 350 words. A fuller response is found below.
In the third week of April 2021, various news media announced that the UK government would be pressing for the development of an ‘anti-viral pill’, which could offer easier and faster support for people infected with a variant or the original wild type Sars-Cov-2 virus. Read the rest of this entry »
As the UK progresses towards the current milestones indicated by the government regarding the changing of social restrictions and the possible development of a different societal set of norms, either temporary or prolonged, it is time to start to categorise risk and future health care plans as our work (in health provision) will be in large part shaped by these developments.
Clearly, the aim of all countries needs to be focussed on the setting up of a future set of plans, strategies to mitigate future zoonotic migrations. But why stop there?
People, environments, and governments are undergoing serious challenges to their futures and part of this hinges on the development of a sustainable approach to health generation. The last 12 months has exposed international vulnerabilities, poor risk management and the associated consequences of a very small pathogen finding a willing host for its journey around the world. Read the rest of this entry »
As the roll out of vaccination and the staged end of lockdown appear to be coalescing into a shift in planning and return to work, there are numerous questions and challenges to be answered and resolved.
First and foremost, is that emerging data suggests that the effects of infection with SARS-CoV-2 are far reaching, extending beyond those with severe acute disease. Specifically, the presence of persistent symptoms after apparent resolution from COVID-19 have frequently been reported throughout the pandemic by individuals variously labelled as “long-haulers and long Covid sufferers”. Incredibly, some evidence is indicating that between as many as 10-30% of survivors of Covid-19 say they still experience symptoms. Just reviewing the implications of this sheer number implies that a review of the mechanisms and treatments is urgently required as this is likely to be a significant drain on health care resource. In the UK in February 2021 a small financial sum of £18.5million has been awarded for 4 research studies. Read the rest of this entry »