CoQ-Gamma E x 60 Soft Gels

Description

A unique formulation from Marty Pall Ph.D. containing high levels of coenzyme Q10, carotenoids, gamma-tocopherol, and gamma-tocotrienol as part of an antioxidant protocol.

Why supplement with CoQ10 with Tocotrienols?

Martin Pall, Ph.D., School of Molecular Biosciences, Washington State University, has identified the NO/ONOO- cycle – the stress-induced increase in the levels of nitric oxide and its oxidant product peroxynitrite, and the biochemical vicious cycle that keeps these levels chronically elevated – as a key mechanism underlying oxidative stress.

Tocotrienols are members of the vitamin E  family and have been shown to strengthen arterial walls and support blood flow through arteries (coronary, carotid, and peripheral).Tocotrienols have been found to support the regulation of cholesterol within normal levels. Rice bran oil provides a high amount of gamma-tocotrienol and gamma-tocopherol for better absorption and utilisation, enhancing the beneficial properties of this formula.

Coenzyme Q10 (CoQ10) is essential for the health of our cells, tissues and organs. It belongs to a family of lipid soluble ubiquinones, present throughout the body, and occurring in the cells of all plants and animals. Among the coenzyme Q compounds that exist in nature, coenzyme Q10 is the predominant form found in humans. It is most concentrated in cells of the heart, liver, kidney and pancreas. The body’s production of CoQ10 peaks around age 20 and then declines. For many decades, supplemental CoQ10 has been used throughout Europe, Asia, and the United States for its support of cellular energy, antioxidant function and cardiovascular health.

CoQ10 plays an essential role in the mitochondrial electron transport chain (ETC), the major metabolic pathway for making energy in every cell of the body. The ETC is the third step in the process of cellular respiration, following glycolysis and the Krebs cycle, the step where most of the energy locked in the original glucose molecule is released. The ETC is a “bucket brigade” of electron-carrying proteins located in the inner membrane of the mitochondria, which transfer electrons from one to another down the chain. This eventually produces water and a gradient through which ATP, our cellular energy currency, is made. CoQ10 functions as an electron carrier in the ETC, linking the various enzymes of the chain. Every pair of electrons processed by the chain must first interact with CoQ10, making the production of ATP dependent on sufficient levels of CoQ10 in the mitochondrial membrane.

Down-regulation of the NO/ONOO- Cycle
Martin Pall, Ph.D., School of Molecular Biosciences, Washington State University, has identified the NO/ONOO- cycle – the stress-induced increase in the levels of nitric oxide and its oxidant product peroxynitrite, and the biochemical vicious cycle that keeps these levels chronically elevated – as a key mechanism underlying oxidative stress. Below are individual and full-spectrum antioxidant preparations that together may assist in down-regulating this NO/ONOO- cycle mechanism. These suggestions are intended as nutritional support, not as a replacement for medical treatment of any condition.

Supportive Recommendations

Avoid obvious sources of pollution, toxins and fumes. Air your house. Consume whole, fresh foods, and minimise all forms of refined sugar and carbohydrates and processed foods. Drink adequate quantities of filtered water.

Cautions & Contraindications

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Keep in a cool, dry place, tightly capped and stored out of reach of children.