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Tag Archive: Culturelle

Lactobacillus GG Modulates Epithelial Cytoprotection through the Nrf2 Pathway

Posted on 03 September 2015 by in News

The idea that bacteria in the gut may have many twists in their skill set to enhance human health has been around for a while. That they may have the capability of inducing a cytoprotective enzyme called Nrf2 in local tissues, which in turn promotes the production of glutathione, detoxification and numerous other health supportive elements has until recently been less well understood.[1]

Nrf2 activation upregulates a regulon of genes including those involved in xenobiotic and reactive oxygen species (ROS) detoxification, as well as pro-restitutive function. This pathway has attracted considerable attention because small molecule inducers of Nrf2 have cytoprotective effects against oxidant and electrophilic environmental stressors.[2],[3] Read the rest of this entry »

A Possible Link Between Early Probiotic Intervention And The Risk Of Neuropsychiatric Disorders Later In Childhood: A Randomized Trial.

Posted on 31 July 2015 by in News

PR-cover-v78_n2.inddFor some time now there has been a growing body of supportive evidence that the relationship between the bacteria in our digestive tract and our central nervous system may not be as tenuous as some may like to think. In a recent study published in Pediatric Research[1] a retrospective review of data in a small but informative group of children, indicates there may be a positive relationship between the use of a well studied probiotic and reduced risk of developing neuropsychiatric illness. Read the rest of this entry »

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