Tag Archive: Vitamin A
A research paper published in the United European Gastroenterology Journal showed that if you are experiencing a period of remission with Cohn’s disease that Vitamin D confers additional benefit in restoring/maintaining appropriate gut permeability.
In this small study – some 27 people were involved, all of whom were determined to be in remission at the time of the oral supplementation with either 2000 iu of vitamin D or a placebo for 90 days. They found, that patients treated with the supplementation were more likely to maintain their intestinal permeability, whereas this deteriorated in the placebo group. Increased intestinal permeability is considered a measure of gut leakiness, which is shown to predict and precede clinical relapse in CD. In addition, patients with the highest blood levels of vitamin D had signs of reduced inflammation (measured by C-reactive protein and antimicrobial peptides), and these patients also reported better quality of life. Read the rest of this entry »
It is well established that high retinoic acid (RA) levels leads to teratogenic effects both in human and experimental models. Brain abnormalities such as microcephaly, impairment of hindbrain development, mandibular and midfacial underdevelopment, and cleft palate are all implicated., Read the rest of this entry »